Two Forms of Tyrosyl-tRNA Synthetase from Pseudomonas aeruginosa: Characterization and Discovery of Inhibitory Compounds

Pseudomonas aeruginosa is a multidrug-resistant (MDR) pathogen and a causative agent of both nosocomial and community-acquired infections. The genes (tyrS and tyrZ) encoding both forms of P. aeruginosa tyrosyl-tRNA synthetase (TyrRS-S and TyrRS-Z) were cloned and the resulting proteins purified. Tyr...

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Bibliografiska uppgifter
I publikationen:SLAS Discov
Huvudupphovsmän: Hughes, Casey A., Gorabi, Varesh, Escamilla, Yaritza, Dean, Frank B., Bullard, James M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7508885/
https://ncbi.nlm.nih.gov/pubmed/32583746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555220934793
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