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Glutaminyl‐tRNA Synthetase from Pseudomonas aeruginosa: Characterization, structure, and development as a screening platform

Pseudomonas aeruginosa has a high potential for developing resistance to multiple antibiotics. The gene (glnS) encoding glutaminyl‐tRNA synthetase (GlnRS) from P. aeruginosa was cloned and the resulting protein characterized. GlnRS was kinetically evaluated and the K (M) and k (cat) (obs), governing...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Escamilla, Yaritza, Hughes, Casey A., Abendroth, Jan, Dranow, David M., Balboa, Samantha, Dean, Frank B., Bullard, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096721/
https://ncbi.nlm.nih.gov/pubmed/31833153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3800
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