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Doxorubicin-induced p53 interferes with mitophagy in cardiac fibroblasts

Anthracyclines are the critical component in a majority of pediatric chemotherapy regimens due to their broad anticancer efficacy. Unfortunately, the vast majority of long-term childhood cancer survivors will develop a chronic health condition caused by their successful treatments and severe cardiac...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Mancilla, T. R., Davis, L. R., Aune, G. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7508395/
https://ncbi.nlm.nih.gov/pubmed/32960902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0238856
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