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β-Hydroxybutyrate inhibits inflammasome activation to attenuate Alzheimer’s disease pathology

Alzheimer’s disease (AD) is a progressive, late-onset dementia with no effective treatment available. Recent studies suggest that AD pathology is driven by age-related changes in metabolism. Alterations in metabolism, such as placing patients on a ketogenic diet, can alter cognition by an unknown me...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Shippy, Daniel C., Wilhelm, Connor, Viharkumar, Patel A., Raife, Thomas J., Ulland, Tyler K.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7507727/
https://ncbi.nlm.nih.gov/pubmed/32958021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01948-5
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