Amyloid-β oligomers set fire to inflammasomes and induce Alzheimer's pathology

Genetic and molecular studies have confirmed the central role of amyloid-β production and fibrillation in the pathogenesis of Alzheimer's disease (AD). However, the pathological pathways from amyloid-β peptide oligomerization to the major pathological hallmarks of AD, such as neurofibrillary ta...

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Bibliographic Details
Published in:J Cell Mol Med
Main Authors: Salminen, Antero, Ojala, Johanna, Suuronen, Tiina, Kaarniranta, Kai, Kauppinen, Anu
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Ltd 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4514104/
https://ncbi.nlm.nih.gov/pubmed/18793350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00496.x
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