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ER stress activates immunosuppressive network: implications for aging and Alzheimer’s disease

The endoplasmic reticulum (ER) contains stress sensors which recognize the accumulation of unfolded proteins within the lumen of ER, and subsequently these transducers stimulate the unfolded protein response (UPR). The ER sensors include the IRE1, PERK, and ATF6 transducers which activate the UPR in...

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Bibliografski detalji
Izdano u:J Mol Med (Berl)
Glavni autori: Salminen, Antero, Kaarniranta, Kai, Kauppinen, Anu
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7220864/
https://ncbi.nlm.nih.gov/pubmed/32279085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-020-01904-z
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