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ER stress activates immunosuppressive network: implications for aging and Alzheimer’s disease

The endoplasmic reticulum (ER) contains stress sensors which recognize the accumulation of unfolded proteins within the lumen of ER, and subsequently these transducers stimulate the unfolded protein response (UPR). The ER sensors include the IRE1, PERK, and ATF6 transducers which activate the UPR in...

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Detalhes bibliográficos
Publicado no:J Mol Med (Berl)
Main Authors: Salminen, Antero, Kaarniranta, Kai, Kauppinen, Anu
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7220864/
https://ncbi.nlm.nih.gov/pubmed/32279085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-020-01904-z
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