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A novel DNAH11 variant segregating in a sibship with heterotaxy and implications for genetic counseling

BACKGROUND: Isomerism or heterotaxy syndrome is the loss of normal asymmetry of the internal thoraco‐abdominal organs in the left‐right axis and is associated with cardiovascular malformations. Mutations within DNAH11 can be associated with primary ciliary dyskinesia and heterotaxy syndromes. METHOD...

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Pubblicato in:Mol Genet Genomic Med
Autori principali: Namavarian, Amirpouyan, Eid, Anas, Goh, Elaine Suk‐Ying, Thakur, Varsha
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7507105/
https://ncbi.nlm.nih.gov/pubmed/32633470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.1358
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