Recombinant Ricin Toxin Binding Subunit B (RTB) Stimulates Production of TNF-α by Mouse Macrophages Through Activation of TLR4 Signaling Pathway

Ricin toxin binding subunit B (RTB) is a galactose-binding lectin protein derived from the beans of the castor oil plant (Ricinus communis). Our previous studies have reported a direct immunomodulatory effect of recombinant RTB, which stimulates RAW264.7 cells to produce cytokines including TNF-α. H...

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Bibliographische Detailangaben
Veröffentlicht in:Front Pharmacol
Hauptverfasser: Xu, Na, Yu, Kaikai, Yu, Haotian, Zhang, Jianxu, Yang, Yang, Dong, Mingxin, Wang, Yan, Chang, Ying, Sun, Yucheng, Hou, Yanguang, Sun, Chengbiao, Wan, Jiayu, Liu, Wensen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7506049/
https://ncbi.nlm.nih.gov/pubmed/33013378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.526129
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