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Group A Streptococcus Infection of the Nasopharynx Requires Proinflammatory Signaling through the Interleukin-1 Receptor

Group A Streptococcus (GAS) is the etiologic agent of numerous high-morbidity and high-mortality diseases. Infections are typically highly proinflammatory. During the invasive infection necrotizing fasciitis, this is in part due to the GAS protease SpeB directly activating interleukin-1β (IL-1β) ind...

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Publicado en:Infect Immun
Main Authors: LaRock, Doris L., Russell, Raedeen, Johnson, Anders F., Wilde, Shyra, LaRock, Christopher N.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7504964/
https://ncbi.nlm.nih.gov/pubmed/32719155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00356-20
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