Ecto-Nucleotide Triphosphate Diphosphohydrolase-2 (NTPDase2) Deletion Increases Acetaminophen-Induced Hepatotoxicity

Ecto-nucleotidase triphosphate diphosphohydrolase-2 (NTPDase2) is an ecto-enzyme that is expressed on portal fibroblasts in the liver that modulates P2 receptor signaling by regulating local concentrations of extracellular ATP and ADP. NTPDase2 has protective properties in liver fibrosis and may imp...

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Publicado en:Int J Mol Sci
Main Authors: Feldbrügge, Linda, Splith, Katrin, Kämmerer, Ines, Richter, Sandra, Riddermann, Anna, Ortiz Galindo, Santiago Andres, Krenzien, Felix, Müller, Tobias, Csizmadia, Eva, Pratschke, Johann, Robson, Simon C., Schmelzle, Moritz
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7504458/
https://ncbi.nlm.nih.gov/pubmed/32825435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21175998
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