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Asymmetric Conservation within Pairs of Co-Occurred Motifs Mediates Weak Direct Binding of Transcription Factors in ChIP-Seq Data

(1) Background: Transcription factors (TFs) are main regulators of eukaryotic gene expression. The cooperative binding to genomic DNA of at least two TFs is the widespread mechanism of transcription regulation. Cooperating TFs can be revealed through the analysis of co-occurrence of their motifs. (2...

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Publicat a:Int J Mol Sci
Autors principals: Levitsky, Victor, Oshchepkov, Dmitry, Zemlyanskaya, Elena, Merkulova, Tatyana
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7504069/
https://ncbi.nlm.nih.gov/pubmed/32825662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21176023
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