ChIP-seq Identification of Weakly Conserved Heart Enhancers

Accurate control of tissue-specific gene expression plays a pivotal role in heart development, but few cardiac transcriptional enhancers have thus far been identified. Extreme non-coding sequence conservation successfully predicts enhancers active in many tissues, but fails to identify substantial n...

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Autores principales: Blow, Matthew J., McCulley, David J., Li, Zirong, Zhang, Tao, Akiyama, Jennifer A., Holt, Amy, Plajzer-Frick, Ingrid, Shoukry, Malak, Wright, Crystal, Chen, Feng, Afzal, Veena, Bristow, James, Ren, Bing, Black, Brian L., Rubin, Edward M., Visel, Axel, Pennacchio, Len A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138496/
https://ncbi.nlm.nih.gov/pubmed/20729851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.650
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