Oxidative Stress, Kinase Activity and Inflammatory Implications in Right Ventricular Hypertrophy and Heart Failure under Hypobaric Hypoxia

High altitude (hypobaric hypoxia) triggers several mechanisms to compensate for the decrease in oxygen bioavailability. One of them is pulmonary artery vasoconstriction and its subsequent pulmonary arterial remodeling. These changes can lead to pulmonary hypertension and the development of right ven...

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Bibliographic Details
Published in:Int J Mol Sci
Main Authors: Pena, Eduardo, Brito, Julio, El Alam, Samia, Siques, Patricia
Format: Artigo
Language:Inglês
Published: MDPI 2020
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7503689/
https://ncbi.nlm.nih.gov/pubmed/32899304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21176421
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