Lower Body Weight in Rats Under Hypobaric Hypoxia Exposure Would Lead to Reduced Right Ventricular Hypertrophy and Increased AMPK Activation

BACKGROUND: Both chronic hypoxia (CH) and long-term chronic intermittent hypoxia (CIH) exposure lead to right ventricular hypertrophy (RVH). Weight loss is an effective intervention to improve cardiac function and energy metabolism in cardiac hypertrophy. Likewise, caloric restriction (CR) also play...

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Pubblicato in:Front Physiol
Autori principali: Flores, Karen, Siques, Patricia, Brito, Julio, Ordenes, Stefany, Arriaza, Karem, Pena, E., León-Velarde, Fabiola, López, Rosario, López de Pablo, Ángel L., Arribas, Silvia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Physiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185171/
https://ncbi.nlm.nih.gov/pubmed/32372974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.00342
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