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Normoxic Tumour Extracellular Vesicles Modulate the Response of Hypoxic Cancer and Stromal Cells to Doxorubicin In Vitro

Extracellular vesicles (EV) secreted in the tumour microenvironment (TME) are emerging as major antagonists of anticancer therapies by orchestrating the therapeutic outcome through altering the behaviour of recipient cells. Recent evidence suggested that chemotherapeutic drugs could be responsible f...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Patras, Laura, Fens, Marcel H. A. M., Vader, Pieter, Barendrecht, Arjan, Sesarman, Alina, Banciu, Manuela, Schiffelers, Raymond
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7503554/
https://ncbi.nlm.nih.gov/pubmed/32824972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21175951
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