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Display of GPI-anchored anti-EGFR nanobodies on extracellular vesicles promotes tumour cell targeting

BACKGROUND: Extracellular vesicles (EVs) are attractive candidate drug delivery systems due to their ability to functionally transport biological cargo to recipient cells. However, the apparent lack of target cell specificity of exogenously administered EVs limits their therapeutic applicability. In...

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Detalhes bibliográficos
Publicado no:J Extracell Vesicles
Main Authors: Kooijmans, Sander A. A., Aleza, Clara Gómez, Roffler, Steve R., van Solinge, Wouter W., Vader, Pieter, Schiffelers, Raymond M.
Formato: Artigo
Idioma:Inglês
Publicado em: Co-Action Publishing 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793259/
https://ncbi.nlm.nih.gov/pubmed/26979463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3402/jev.v5.31053
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