Display of GPI-anchored anti-EGFR nanobodies on extracellular vesicles promotes tumour cell targeting

BACKGROUND: Extracellular vesicles (EVs) are attractive candidate drug delivery systems due to their ability to functionally transport biological cargo to recipient cells. However, the apparent lack of target cell specificity of exogenously administered EVs limits their therapeutic applicability. In...

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Vydáno v:J Extracell Vesicles
Hlavní autoři: Kooijmans, Sander A. A., Aleza, Clara Gómez, Roffler, Steve R., van Solinge, Wouter W., Vader, Pieter, Schiffelers, Raymond M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Co-Action Publishing 2016
Témata:
Short Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793259/
https://ncbi.nlm.nih.gov/pubmed/26979463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3402/jev.v5.31053
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