Display of GPI-anchored anti-EGFR nanobodies on extracellular vesicles promotes tumour cell targeting

BACKGROUND: Extracellular vesicles (EVs) are attractive candidate drug delivery systems due to their ability to functionally transport biological cargo to recipient cells. However, the apparent lack of target cell specificity of exogenously administered EVs limits their therapeutic applicability. In...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Extracell Vesicles
Hauptverfasser: Kooijmans, Sander A. A., Aleza, Clara Gómez, Roffler, Steve R., van Solinge, Wouter W., Vader, Pieter, Schiffelers, Raymond M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Co-Action Publishing 2016
Schlagworte:
Short Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4793259/
https://ncbi.nlm.nih.gov/pubmed/26979463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3402/jev.v5.31053
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