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Endoplasmic Reticulum Stress and Unfolded Protein Response in Neurodegenerative Diseases

The endoplasmic reticulum (ER) is an important organelle involved in protein quality control and cellular homeostasis. The accumulation of unfolded proteins leads to an ER stress, followed by an adaptive response via the activation of the unfolded protein response (UPR), PKR-like ER kinase (PERK), i...

詳細記述

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書誌詳細
出版年:Int J Mol Sci
主要な著者: Ghemrawi, Rose, Khair, Mostafa
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7503386/
https://ncbi.nlm.nih.gov/pubmed/32854418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21176127
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