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Endoplasmic Reticulum Stress and Unfolded Protein Response in Neurodegenerative Diseases

The endoplasmic reticulum (ER) is an important organelle involved in protein quality control and cellular homeostasis. The accumulation of unfolded proteins leads to an ER stress, followed by an adaptive response via the activation of the unfolded protein response (UPR), PKR-like ER kinase (PERK), i...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ghemrawi, Rose, Khair, Mostafa
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7503386/
https://ncbi.nlm.nih.gov/pubmed/32854418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21176127
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