Concordance of CSF measures of Alzheimer's pathology with amyloid PET status in a preclinical cohort: A comparison of Lumipulse and established immunoassays

INTRODUCTION: We assessed the concordance of cerebrospinal fluid (CSF) amyloid beta (Aβ) and tau measured on the fully automated Lumipulse platform with pre‐symptomatic Alzheimer's disease (AD) pathology on amyloid positron emission tomography (PET). METHODS: In 72 individuals from the Insight...

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Détails bibliographiques
Publié dans:Alzheimers Dement (Amst)
Auteurs principaux: Keshavan, Ashvini, Wellington, Henrietta, Chen, Zhongbo, Khatun, Ayesha, Chapman, Miles, Hart, Melanie, Cash, David M., Coath, William, Parker, Thomas D., Buchanan, Sarah M., Keuss, Sarah E., Harris, Matthew J., Murray‐Smith, Heidi, Heslegrave, Amanda, Fox, Nick C., Zetterberg, Henrik, Schott, Jonathan M.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Cerebrospinal Fluid Biomarkers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7503103/
https://ncbi.nlm.nih.gov/pubmed/32999915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dad2.12097
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