STING Mediates Lupus via the Activation of Conventional Dendritic Cell Maturation and Plasmacytoid Dendritic Cell Differentiation

Signaling through stimulator of interferon genes (STING) leads to the production of type I interferons (IFN-Is) and inflammatory cytokines. A gain-of-function mutation in STING was identified in an autoinflammatory disease (STING-associated vasculopathy with onset in infancy; SAVI). The expression o...

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Publicado no:iScience
Main Authors: Thim-uam, Arthid, Prabakaran, Thaneas, Tansakul, Mookmanee, Makjaroen, Jiradej, Wongkongkathep, Piriya, Chantaravisoot, Naphat, Saethang, Thammakorn, Leelahavanichkul, Asada, Benjachat, Thitima, Paludan, Søren, Pisitkun, Trairak, Pisitkun, Prapaporn
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7502826/
https://ncbi.nlm.nih.gov/pubmed/33083760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101530
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