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Characterization of the anti-CD22 targeted therapy, moxetumomab pasudotox, for B-cell precursor acute lymphoblastic leukemia

Moxetumomab pasudotox is a second-generation recombinant immunotoxin against CD22 on B-cell lineages. Antileukemic activity has been demonstrated in children with chemotherapy-refractory B-cell precursor acute lymphoblastic leukemia (BCP-ALL), with variable responses. Here, we report in vitro and in...

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Bibliografiska uppgifter
I publikationen:Pediatr Blood Cancer
Huvudupphovsmän: Kinjyo, Ichiko, Matlawska-Wasowska, Ksenia, Chen, Xiaoru, Monks, Noel R., Burke, Patricia, Winter, Stuart S., Wilson, Bridget S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501879/
https://ncbi.nlm.nih.gov/pubmed/28449314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.26604
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