Exome Sequencing Identifies A Nonsense Variant in DAO Associated With Reduced Energy Expenditure in American Indians

BACKGROUND: Obesity and energy expenditure (EE) are heritable and genetic variants influencing EE may contribute to the development of obesity. We sought to identify genetic variants that affect EE in American Indians, an ethnic group with high prevalence of obesity. METHODS: Whole-exome sequencing...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Clin Endocrinol Metab
Main Authors: Piaggi, Paolo, Köroğlu, Çiğdem, Nair, Anup K, Sutherland, Jeff, Muller, Yunhua L, Kumar, Pankaj, Hsueh, Wen-Chi, Kobes, Sayuko, Shuldiner, Alan R, Kim, Hye In, Gosalia, Nehal, Van Hout, Cristopher V, Jones, Marcus, Knowler, William C, Krakoff, Jonathan, Hanson, Robert L, Bogardus, Clifton, Baier, Leslie J
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2020
נושאים:
Clinical Research Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501742/
https://ncbi.nlm.nih.gov/pubmed/32818236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/clinem/dgaa548
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