Rapid and economical drug resistance profiling with Nanopore MinION for clinical specimens with low bacillary burden of Mycobacterium tuberculosis

OBJECTIVE: We designed and tested a Nanopore sequencing panel for direct tuberculosis drug resistance profiling. The panel targeted 10 resistance-associated loci. We assessed the feasibility of amplifying and sequencing these loci from 23 clinical specimens with low bacillary burden. RESULTS: At lea...

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Publicat a:BMC Res Notes
Autors principals: Chan, Wai Sing, Au, Chun Hang, Chung, Yvonne, Leung, Henry Chi Ming, Ho, Dona N., Wong, Elaine Yue Ling, Lam, Tak Wah, Chan, Tsun Leung, Ma, Edmond Shiu Kwan, Tang, Bone Siu Fai
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research Note
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501614/
https://ncbi.nlm.nih.gov/pubmed/32948225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-020-05287-9
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