Rapid and economical drug resistance profiling with Nanopore MinION for clinical specimens with low bacillary burden of Mycobacterium tuberculosis

OBJECTIVE: We designed and tested a Nanopore sequencing panel for direct tuberculosis drug resistance profiling. The panel targeted 10 resistance-associated loci. We assessed the feasibility of amplifying and sequencing these loci from 23 clinical specimens with low bacillary burden. RESULTS: At lea...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :BMC Res Notes
Главные авторы: Chan, Wai Sing, Au, Chun Hang, Chung, Yvonne, Leung, Henry Chi Ming, Ho, Dona N., Wong, Elaine Yue Ling, Lam, Tak Wah, Chan, Tsun Leung, Ma, Edmond Shiu Kwan, Tang, Bone Siu Fai
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2020
Предметы:
Research Note
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501614/
https://ncbi.nlm.nih.gov/pubmed/32948225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-020-05287-9
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы