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Recent advancements in PARP inhibitors-based targeted cancer therapy
Poly(ADP-ribose) polymerase inhibitors (PARPi) are a new class of agents with unparalleled clinical achievement for driving synthetic lethality in BRCA-deficient cancers. Recent FDA approval of PARPi has motivated clinical trials centered around the optimization of PARPi-associated therapies in a va...
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| Publicado en: | Precis Clin Med |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7501589/ https://ncbi.nlm.nih.gov/pubmed/32983586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/pcmedi/pbaa030 |
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