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Deep exploration of PARP inhibitors in breast cancer: monotherapy and combination therapy
OBJECTIVE: Nearly 5% of patients with breast cancer carry germline BRCA mutations, which are more common in triple-negative breast cancer (TNBC). Previous clinical trials demonstrated the therapeutic efficacy of poly (ADP-ribose) polymerase inhibitors (PARPis) against BRCA-mutated metastatic breast...
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| Publicado no: | J Int Med Res |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8164563/ https://ncbi.nlm.nih.gov/pubmed/33541181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0300060521991019 |
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