SPT6-driven error-free DNA repair safeguards genomic stability of glioblastoma cancer stem-like cells

Glioblastoma cancer-stem like cells (GSCs) display marked resistance to ionizing radiation (IR), a standard of care for glioblastoma patients. Mechanisms underpinning radio-resistance of GSCs remain largely unknown. Chromatin state and the accessibility of DNA lesions to DNA repair machineries are c...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Obara, Elisabeth Anne Adanma, Aguilar-Morante, Diana, Rasmussen, Rikke Darling, Frias, Alex, Vitting-Serup, Kristoffer, Lim, Yi Chieh, Elbæk, Kirstine Juul, Pedersen, Henriette, Vardouli, Lina, Jensen, Kamilla Ellermann, Skjoth-Rasmussen, Jane, Brennum, Jannick, Tuckova, Lucie, Strauss, Robert, Dinant, Christoffel, Bartek, Jiri, Hamerlik, Petra
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501306/
https://ncbi.nlm.nih.gov/pubmed/32948765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18549-8
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