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CSIG-05. THE HISTONE CHAPERONE Spt6 IS REQUIRED FOR GENOMIC STABILITY OF GLIOBLASTOMA CANCER STEM-LIKE CELLS

Rampant genomic instability is a hallmark of glioblastoma (GBM). Despite recent advances in our understanding of this deadly disease, molecular mechanism contributing to treatment resistance are poorly understood. Histone chaperones regulate chromatin structure and gene expression through interactio...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Rasmussen, Rikke, Obara, Elisabeth A, Vitting-Serup, Kristoffer, Jensen, Kamilla E, Skjøth-Rasmussen, Jane, Brennum, Jannick, Bartek, Jiri, Hamerlik, Petra
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692917/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.200
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