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Association of APOE e2 genotype with Alzheimer’s and non-Alzheimer’s neurodegenerative pathologies

The apolipoprotein E (APOE) gene contains both the major common risk variant for late onset Alzheimer’s disease (AD), e4, and the major neuroprotective variant, e2. Here we examine the association of APOE e2 with multiple neurodegenerative pathologies, leveraging the NACC v. 10 database of 1557 brai...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Goldberg, Terry E., Huey, Edward D., Devanand, D. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501268/
https://ncbi.nlm.nih.gov/pubmed/32948752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18198-x
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