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Multiplex flow magnetic tweezers reveal rare enzymatic events with single molecule precision

The application of forces and torques on the single molecule level has transformed our understanding of the dynamic properties of biomolecules, but rare intermediates have remained difficult to characterize due to limited throughput. Here, we describe a method that provides a 100-fold improvement in...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Agarwal, Rohit, Duderstadt, Karl E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501243/
https://ncbi.nlm.nih.gov/pubmed/32948754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18456-y
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