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TOK channels use the two gates in classical K(+) channels to achieve outward rectification

TOKs are outwardly rectifying K(+) channels in fungi with two pore-loops and eight transmembrane spans. Here, we describe the TOKs from four pathogens that cause the majority of life-threatening fungal infections in humans. These TOKs pass large currents only in the outward direction like the canoni...

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Détails bibliographiques
Publié dans:FASEB J
Auteurs principaux: Lewis, Anthony, McCrossan, Zoe A., Manville, Rían W., Popa, M. Oana, Cuello, Luis G., Goldstein, Steve A. N.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501187/
https://ncbi.nlm.nih.gov/pubmed/32519783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202000545R
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