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TOK channels use the two gates in classical K(+) channels to achieve outward rectification

TOKs are outwardly rectifying K(+) channels in fungi with two pore-loops and eight transmembrane spans. Here, we describe the TOKs from four pathogens that cause the majority of life-threatening fungal infections in humans. These TOKs pass large currents only in the outward direction like the canoni...

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Podrobná bibliografie
Vydáno v:FASEB J
Hlavní autoři: Lewis, Anthony, McCrossan, Zoe A., Manville, Rían W., Popa, M. Oana, Cuello, Luis G., Goldstein, Steve A. N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501187/
https://ncbi.nlm.nih.gov/pubmed/32519783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202000545R
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