Post-tetanic potentiation lowers the energy barrier for synaptic vesicle fusion independently of Synaptotagmin-1

Previously, we showed that modulation of the energy barrier for synaptic vesicle fusion boosts release rates supralinearly (Schotten, 2015). Here we show that mouse hippocampal synapses employ this principle to trigger Ca(2+)-dependent vesicle release and post-tetanic potentiation (PTP). We assess e...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Huson, Vincent, Meijer, Marieke, Dekker, Rien, ter Veer, Mirelle, Ruiter, Marvin, van Weering, Jan RT, Verhage, Matthijs, Cornelisse, Lennart Niels
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7500951/
https://ncbi.nlm.nih.gov/pubmed/32831174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55713
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