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Synaptotagmin-1 enables frequency coding by suppressing asynchronous release in a temperature dependent manner

To support frequency-coded information transfer, mammalian synapses tightly synchronize neurotransmitter release to action potentials (APs). However, release desynchronizes during AP trains, especially at room temperature. Here we show that suppression of asynchronous release by Synaptotagmin-1 (Syt...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Huson, Vincent, van Boven, Maaike A., Stuefer, Alexia, Verhage, Matthijs, Cornelisse, L. Niels
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683208/
https://ncbi.nlm.nih.gov/pubmed/31383906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47487-9
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