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RELATe enables genome-scale engineering in fungal genomics

CRISPR-Cas9–based screening with single-guide RNA (sgRNA) libraries has emerged as a revolutionary tool for comprehensive analysis of genetic elements. However, genome-scale sgRNA libraries are currently available only in a few model organisms. The traditional approach is to synthesize thousands to...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Li, Zhongming, Kim, Kwang Sik
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7500931/
https://ncbi.nlm.nih.gov/pubmed/32948588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abb8783
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