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Genome-scale modeling using flux ratio constraints to enable metabolic engineering of clostridial metabolism in silico

BACKGROUND: Genome-scale metabolic networks and flux models are an effective platform for linking an organism genotype to its phenotype. However, few modeling approaches offer predictive capabilities to evaluate potential metabolic engineering strategies in silico. RESULTS: A new method called “flux...

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Hlavní autoři: McAnulty, Michael J, Yen, Jiun Y, Freedman, Benjamin G, Senger, Ryan S
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495714/
https://ncbi.nlm.nih.gov/pubmed/22583864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-42
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