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In silico co-factor balance estimation using constraint-based modelling informs metabolic engineering in Escherichia coli

In the growing field of metabolic engineering, where cells are treated as ‘factories’ that synthesize industrial compounds, it is essential to consider the ability of the cells’ native metabolism to accommodate the demands of synthetic pathways, as these pathways will alter the homeostasis of cellul...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: de Arroyo Garcia, Laura, Jones, Patrik R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7440669/
https://ncbi.nlm.nih.gov/pubmed/32776925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008125
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