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Generation of Magnesium Pentafluoropropen-2-olate from Hexafluoroisopropanol and Synthesis of 2,2,4,4,4-Pentafluoro-3,3-dihydroxyketones

2,2,4,4,4-Pentafluoro-3,3-dihydroxyketones are valuable precursors to difluoroenolates, following fragmentation during the release of trifluoroacetate; however, there are few synthetic strategies to prepare this unique class of compound. We have addressed this issue and report a mild, two-step synth...

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Pubblicato in:J Org Chem
Autori principali: Hazlitt, Robert A., Tran, Que-Lynn, Sowaileh, Munia F., Colby, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7500852/
https://ncbi.nlm.nih.gov/pubmed/28107014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.6b02863
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