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BioPETsurv: Methodology and open source software to evaluate biomarkers for prognostic enrichment of time-to-event clinical trials

Biomarkers can be used to enrich a clinical trial for patients at higher risk for an outcome, a strategy termed "prognostic enrichment." Methodology is needed to evaluate biomarkers for prognostic enrichment of trials with time-to-event endpoints such as survival. Key considerations when c...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cheng, Si, Kerr, Kathleen F., Thiessen-Philbrook, Heather, Coca, Steven G., Parikh, Chirag R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7500596/
https://ncbi.nlm.nih.gov/pubmed/32946505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0239486
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