Evaluating biomarkers for prognostic enrichment of clinical trials

BACKGROUND/AIMS: A potential use of biomarkers is to assist in prognostic enrichment of clinical trials, where only patients at relatively higher risk for an outcome of interest are eligible for the trial. We investigated methods for evaluating biomarkers for prognostic enrichment. METHODS: We ident...

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Опубликовано в: :Clin Trials
Главные авторы: Kerr, Kathleen F, Roth, Jeremy, Zhu, Kehao, Thiessen-Philbrook, Heather, Meisner, Allison, Wilson, Francis Perry, Coca, Steven, Parikh, Chirag R
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714681/
https://ncbi.nlm.nih.gov/pubmed/28795578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774517723588
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