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Genetic Reprogramming of the Ergot Alkaloid Pathway of Metarhizium brunneum

Ergot alkaloids are important specialized fungal metabolites that are used to make potent pharmaceuticals for neurological diseases and disorders. Lysergic acid (LA) and dihydrolysergic acid (DHLA) are desirable lead compounds for pharmaceutical semisynthesis but are typically transient intermediate...

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Bibliografische gegevens
Gepubliceerd in:Appl Environ Microbiol
Hoofdauteurs: Davis, Kyle A., Sampson, Jessi K., Panaccione, Daniel G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7499049/
https://ncbi.nlm.nih.gov/pubmed/32769181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01251-20
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