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Genetic Reprogramming of the Ergot Alkaloid Pathway of Metarhizium brunneum

Ergot alkaloids are important specialized fungal metabolites that are used to make potent pharmaceuticals for neurological diseases and disorders. Lysergic acid (LA) and dihydrolysergic acid (DHLA) are desirable lead compounds for pharmaceutical semisynthesis but are typically transient intermediate...

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書目詳細資料
發表在:Appl Environ Microbiol
Main Authors: Davis, Kyle A., Sampson, Jessi K., Panaccione, Daniel G.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7499049/
https://ncbi.nlm.nih.gov/pubmed/32769181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01251-20
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