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Genetic Reprogramming of the Ergot Alkaloid Pathway of Metarhizium brunneum

Ergot alkaloids are important specialized fungal metabolites that are used to make potent pharmaceuticals for neurological diseases and disorders. Lysergic acid (LA) and dihydrolysergic acid (DHLA) are desirable lead compounds for pharmaceutical semisynthesis but are typically transient intermediate...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Davis, Kyle A., Sampson, Jessi K., Panaccione, Daniel G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7499049/
https://ncbi.nlm.nih.gov/pubmed/32769181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01251-20
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