Hypoxic Tumor-Derived Exosomal Long Noncoding RNA UCA1 Promotes Angiogenesis via miR-96-5p/AMOTL2 in Pancreatic Cancer

The hypoxic microenvironment, an important feature of solid tumors, promotes tumor cells to release exosomes and enhances tumor angiogenesis. However, the detailed functions of hypoxic exosomes and the mechanisms underlying their effects in pancreatic cancer (PC) remain mysterious. Here, we observed...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Guo, Zengya, Wang, Xiaofeng, Yang, Yuhan, Chen, Weiwei, Zhang, Kundong, Teng, Buwei, Huang, Chen, Zhao, Qian, Qiu, Zhengjun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498711/
https://ncbi.nlm.nih.gov/pubmed/32942233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.08.021
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