Impact of arginine therapy on mitochondrial function in children with sickle cell disease during vaso-occlusive pain

Altered mitochondrial function occurs in sickle cell disease (SCD), due in part to low nitric oxide (NO) bioavailability. Arginine, the substrate for NO production, becomes acutely deficient in SCD patients with vaso-occlusive pain episodes (VOE). To determine if arginine improves mitochondrial func...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Blood
Autors principals: Morris, Claudia R., Brown, Lou Ann S., Reynolds, Michael, Dampier, Carlton D., Lane, Peter A., Watt, Amanda, Kumari, Polly, Harris, Frank, Manoranjithan, Shaminy, Mendis, Reshika D., Figueroa, Janet, Shiva, Sruti
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2020
Matèries:
Clinical Trials and Observations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498366/
https://ncbi.nlm.nih.gov/pubmed/32384147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019003672
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars