Impact of arginine therapy on mitochondrial function in children with sickle cell disease during vaso-occlusive pain

Altered mitochondrial function occurs in sickle cell disease (SCD), due in part to low nitric oxide (NO) bioavailability. Arginine, the substrate for NO production, becomes acutely deficient in SCD patients with vaso-occlusive pain episodes (VOE). To determine if arginine improves mitochondrial func...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Blood
Autores principales: Morris, Claudia R., Brown, Lou Ann S., Reynolds, Michael, Dampier, Carlton D., Lane, Peter A., Watt, Amanda, Kumari, Polly, Harris, Frank, Manoranjithan, Shaminy, Mendis, Reshika D., Figueroa, Janet, Shiva, Sruti
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2020
Materias:
Clinical Trials and Observations
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498366/
https://ncbi.nlm.nih.gov/pubmed/32384147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019003672
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares