Impact of arginine therapy on mitochondrial function in children with sickle cell disease during vaso-occlusive pain

Altered mitochondrial function occurs in sickle cell disease (SCD), due in part to low nitric oxide (NO) bioavailability. Arginine, the substrate for NO production, becomes acutely deficient in SCD patients with vaso-occlusive pain episodes (VOE). To determine if arginine improves mitochondrial func...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Blood
Main Authors: Morris, Claudia R., Brown, Lou Ann S., Reynolds, Michael, Dampier, Carlton D., Lane, Peter A., Watt, Amanda, Kumari, Polly, Harris, Frank, Manoranjithan, Shaminy, Mendis, Reshika D., Figueroa, Janet, Shiva, Sruti
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Clinical Trials and Observations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498366/
https://ncbi.nlm.nih.gov/pubmed/32384147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019003672
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados