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Structural basis of DNA binding to human YB-1 cold shock domain regulated by phosphorylation
Human Y-box binding protein 1 (YB-1) is a multifunctional protein and overexpressed in many types of cancer. It specifically recognizes DNA/RNA through a cold shock domain (CSD) and regulates nucleic acid metabolism. The C-terminal extension of CSD and the phosphorylation of S102 are indispensable f...
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| Published in: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7498358/ https://ncbi.nlm.nih.gov/pubmed/32710623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa619 |
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