The chromatin-binding protein PHF6 functions as an E3 ubiquitin ligase of H2BK120 via H2BK12Ac recognition for activation of trophectodermal genes

Epigenetic regulation is important for establishing lineage-specific gene expression during early development. Although signaling pathways have been well-studied for regulation of trophectoderm reprogramming, epigenetic regulation of trophectodermal genes with histone modification dynamics have been...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Oh, Sungryong, Boo, Kyungjin, Kim, Jaebeom, Baek, Seon Ah, Jeon, Yoon, You, Junghyun, Lee, Ho, Choi, Hee-Jung, Park, Daechan, Lee, Ji Min, Baek, Sung Hee
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Gene regulation, Chromatin and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498345/
https://ncbi.nlm.nih.gov/pubmed/32735658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa626
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