Atypical plant homeodomain of UBR7 functions as an H2BK120Ub ligase and breast tumor suppressor

The roles of Plant Homeodomain (PHD) fingers in catalysis of histone modifications are unknown. We demonstrated that the PHD finger of Ubiquitin Protein Ligase E3 Component N-Recognin7 (UBR7) harbors E3 ubiquitin ligase activity toward monoubiquitination of histone H2B at lysine120 (H2BK120Ub). Puri...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Adhikary, Santanu, Chakravarti, Deepavali, Terranova, Christopher, Sengupta, Isha, Maitituoheti, Mayinuer, Dasgupta, Anirban, Srivastava, Dushyant Kumar, Ma, Junsheng, Raman, Ayush T., Tarco, Emily, Sahin, Aysegul A., Bassett, Roland, Yang, Fei, Tapia, Coya, Roy, Siddhartha, Rai, Kunal, Das, Chandrima
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6438984/
https://ncbi.nlm.nih.gov/pubmed/30923315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08986-5
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados