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Uncoupling gene expression noise along the central dogma using genome engineered human cell lines

Eukaryotic protein synthesis is an inherently stochastic process. This stochasticity stems not only from variations in cell content between cells but also from thermodynamic fluctuations in a single cell. Ultimately, these inherently stochastic processes manifest as noise in gene expression, where e...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Quarton, Tyler, Kang, Taek, Papakis, Vasileios, Nguyen, Khai, Nowak, Chance, Li, Yi, Bleris, Leonidas
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498316/
https://ncbi.nlm.nih.gov/pubmed/32810265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa668
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