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Predictions and analyses of RNA nearest neighbor parameters for modified nucleotides

The most popular RNA secondary structure prediction programs utilize free energy (ΔG°(37)) minimization and rely upon thermodynamic parameters from the nearest neighbor (NN) model. Experimental parameters are derived from a series of optical melting experiments; however, acquiring enough melt data t...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Hopfinger, Melissa C, Kirkpatrick, Charles C, Znosko, Brent M
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498315/
https://ncbi.nlm.nih.gov/pubmed/32810273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa654
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